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Best CoQ10 for Ultimate Cardiovascular Health in 2023

  • Hermina Drah
  • December 30, 2021
coenzyme q10

Poor heart health is one of the leading causes of various health issues and premature death. Fortunately, coenzyme Q10 supplements are here to fortify your cardiovascular system and maintain its health.

Let’s check out some of the best CoQ10 products available.

Top CoQ10 Supplements

We’re committed to providing you with the best products available. If you purchase through one of the links on our site, we may earn a commission. Read our full Affiliate Disclosure.

BulkSupplements.com Coenzyme Q10 (CoQ10)

BulkSupplements.com Coenzyme Q10 (CoQ10) BulkSupplements.com Review

The Overall Best CoQ10 Option

  • Easily dissolves
  • It comes in a variety of sizes
  • Free of yeast, sugar, gluten, and additives
star 10
$22.96 for 0.4 oz Read Review
Visit Site

Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support

Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support Life Extension Review

Best Product With Ubiquinol

  • High absorption rate
  • Sugar-free formula
  • Easy-to-swallow capsules
star 9.9
$46.50 for 60 softgels Read Review
Visit Site

Garden of Life RAW CoQ10

Garden of Life RAW CoQ10 Garden of Life Logo

Top Choice With Omega 3-6-9 Lipid Delivery System

  • Free of binders and fillers
  • Includes omega 3-6-9 matrix from cold-pressed raw chia seed oil
  • Supports digestion
star 9.8
$56.99 for 60 capsules Read Review
Visit Site

Nature Made CoQ10

Nature Made CoQ10 Nature Made Logo

Best for Statin Users

  • Excellent choice for statin users
  • Gluten-free
  • Preservative-free
star 9.7
$25.59 for 40 softgels Read Review
Visit Site

Nature's Bounty Co Q-10

Nature's Bounty Co Q-10 Nature's Bounty Logo

Top Rapid-Release CoQ10 Supplement

  • Laboratory-tested formula
  • Natural colors
  • Sodium-free
star 9.6
$16.95 for 75 softgels Read Review
Visit Site

Solgar Vegetarian CoQ-10

Solgar Vegetarian CoQ-10 Solgar

Top Choice for Vegans

  • Suitable for people with sensitivities
  • Sweetener-free
  • Wheat-free
star 9.5
$13.34 for 30 capsules Read Review
Visit Site

Bluebonnet Nutrition CellularActive CoQ10

Bluebonnet Nutrition CellularActive CoQ10 Bluebonnet

Best Allergen-Free Option

  • Vegetarian-friendly
  • Made with Kaneka Ubiquinol
  • Non-GMO
star 9.4
$12.76 for 30 softgels Read Review
Visit Site

Qunol Ultra CoQ10

Qunol Ultra CoQ10 Qunol

The Most Absorbable Supplement

  • Three times better absorption
  • Dairy-free
  • Boosts skin health
star 9.3
$29.97 for 120 softgels Read Review
Visit Site

Natural Factors Ubiquinol Active CoQ10

Natural Factors Ubiquinol Active CoQ10 Natural Factors

Best for Age-Related CoQ10 Loss

  • Lab-tested for quality
  • Includes organic flaxseed oil
  • Reduces inflammation
star 9.2
$14.04 for 30 softgels Read Review
Visit Site

21st Century Co Q-10

21st Century Co Q-10 21st Century

Best for Energy

  • Small, easy to swallow capsules
  • Three-month supply
  • Numerous favorable customer reviews
star 9.1
$15.90 for 90 softgels Read Review
Visit Site

The Ultimate CoQ10 Reviews

The section below gives a detailed insight into each of the top-rated products, discussing their main features, benefits, pros, and cons.

BulkSupplements.com Coenzyme Q10 (CoQ10)

BulkSupplements.com Coenzyme Q10 (CoQ10) BulkSupplements.com Coenzyme Q10 (CoQ10)
star 10

The Overall Best CoQ10 Option

  • Form: Powder
  • Number of servings: 50
  • Ingredients: Coenzyme Q10 (ubiquinone)
  • CoQ10 content: 200 mg
  • Shipping policy: Free shipping on orders over $49
$22.96 for 0.4 oz
Visit Site Back To List

If you’re looking for the best coenzyme Q10 brand, look no further. BulkSupplements.com offers the pure CoQ10 in packages ranging from 0.4 oz up to the colossal 11lbs. 

It’s one of those rare supplements that features only one ingredient and nothing else. And it’s free of gluten, yeast, sugar, and other potentially harmful additives. 

With 200 mg of pure coenzyme Q10 per serving, this product offers a wide array of functions. It supports liver function, alleviates muscle and joint pain, promotes cardiovascular and brain health, helps manage a healthy weight, etc.

Furthermore, consumers highlight this top-rated CoQ10 product’s ability to support brain health and fortify immune function. They report feeling more clear-minded, focused, and energized after only two months of continuous use.


Pros

  • + Easily dissolves
  • + It comes in a variety of sizes
  • + Free of yeast, sugar, gluten, and additives

Cons

  • − Some consumers may find the powder messy and inconvenient

Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support

Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support
star 9.9

Best Product With Ubiquinol

  • Form: Softgel 9.9
  • Number of servings: 60
  • Ingredients: Ubiquinol, PrimaVie Shilajit fulvic acid complex, sunflower oil, gelatin, glycerin, beeswax, purified water, annatto color, lecithin
  • CoQ10 content: 100 mg
  • Shipping policy: Free shipping on AutoShip orders and one-time orders over $50
$46.50 for 60 softgels
Visit Site Back To List

The Life Extension Super Ubiquinol CoQ10 is an ultra-absorbable supplement for heart and brain health. What sets it apart from other CoQ10 products is its superior bioavailability. 

The reason for this is that this product uses ubiquinol instead of ubiquinone, a CoQ10 form commonly used in competitor products.

Ubiquinol is likely the best form of CoQ10, as it’s about eight times more bioavailable than ubiquinone and other CoQ10 forms. Therefore, the body absorbs it better, and you can reap all the benefits much faster.

Furthermore, Super Ubiquinol CoQ10 contains shilajit, a healing nutrient from the Himalayas that further stimulates CoQ10 absorption, supports cellular energy production, and improves cardiovascular health. 

According to some of the CoQ10 reviews, this CoQ10 product can provide you with increased energy levels and better heart health in just over two months. Users also report increased focus levels and superb cholesterol management.


Pros

  • + High absorption rate
  • + Sugar-free formula
  • + Easy-to-swallow capsules

Cons

  • − Contains ingredients other than CoQ10

Garden of Life RAW CoQ10

Garden of Life RAW CoQ10 Garden of Life RAW CoQ10
star 9.8

Top Choice With Omega 3-6-9 Lipid Delivery System

  • Form: Vegan capsules
  • Number of servings: 60
  • Ingredients: CoQ10, RAW cold-pressed chia seed oil, RAW organic fruit and vegetable blend, RAW probiotic blend
  • CoQ10 content: 200 mg
  • Shipping policy: Free shipping on orders of a minimum of $25 within the US
$56.99 for 60 capsules
Visit Site Back To List

If you’re on the lookout for the best CoQ10 on the market with a unique delivery system and high absorbability, Garden Life’s got you covered. 

Raw chia seed oil and omega 3-6-9 matrix enhance and speed up CoQ10 absorption, making this premium supplement more effective more quickly.

Not only is this supplement rich in antioxidants and CoQ10, but it also provides a heap of beneficial nutrients from 23 organic veggies and fruits. Each serving grants you a 30-mg-blend of organic beetroot, strawberries, broccoli, asparagus, and other nutrient-dense greens.

RAW CoQ10’s ingredient combination allows it to provide excellent heart health and cellular energy boost. Furthermore, the best CoQ10 supplement reviews report this CoQ10 product can help digestion (due to the inclusion of live probiotics), clear up the skin, and help with weight management.


Pros

  • + Free of binders and fillers
  • + Includes omega 3-6-9 matrix from cold-pressed raw chia seed oil
  • + Supports digestion

Cons

  • − It requires continuous use for the results to show

Nature Made CoQ10

Nature Made CoQ10 Nature Made CoQ10
star 9.7

Best for Statin Users

  • Form: Softgel
  • Number of servings: 40
  • Ingredients: Coenzyme Q10 (ubidecarenone), soybean oil, glycerin, gelatin, rapeseed lecithin, water
  • CoQ10 content: 100 mg
  • Shipping policy: Free shipping on orders over $25
$25.59 for 40 softgels
Visit Site Back To List

There are many reasons why this supplement was dubbed the best CoQ10 supplement of 2020 in our book. First, this product is USP-verified, meaning it’s potent, safe, and doesn’t contain harmful levels of microbes, heavy metals, pesticides, etc.

Moreover, it’s free from added colors, artificial flavors, preservatives, and gluten, making it safe for even the most sensitive consumers.

Most importantly, this product is excellent for those on statin therapy. This cholesterol-lowering drug impairs natural CoQ10 production, leading to low CoQ10 levels. Luckily, Nature Made CoQ10 effectively replenishes it, preventing deficiency.  

However, you should bear in mind that this product contains soy, a common allergen.


Pros

  • + Excellent choice for statin users
  • + Gluten-free
  • + Preservative-free

Cons

  • − Contains soy

Nature's Bounty Co Q-10

Nature's Bounty Co Q-10 Nature's Bounty Co Q-10
star 9.6

Top Rapid-Release CoQ10 Supplement

  • Form: Softgel
  • Number of servings: 75
  • Ingredients: Q-SorbTM Coenzyme Q-10, rice bran oil, vegetable glycerin, gelatin, titanium dioxide color, soy lecithin
  • CoQ10 content: 100 mg
  • Shipping policy: Free shipping with Amazon Prime; occasional limited-time deals on iHerb (e.g., free shipping on orders over $20)
$16.95 for 75 softgels
Visit Site Back To List

Nature’s Bounty produced one of the top-rated CoQ10 supplements for cardiovascular health on the market. What makes it unique are the easy-to-swallow rapid-release softgels that enable the quick release of CoQ10 into your system.

Even though this supplement doesn’t contain the best form of coenzyme Q10, ubiquinol, it offers a hefty dose of Q-Sorb—a good source of the coQ10. So not only is this an excellent choice for people who need cardiovascular health support, but it’s also suitable for inflammation relief.

Furthermore, this product contains no GMOs, artificial colors, flavors, sugar, dairy, or yeast.  However, it contains soy, which makes it unsuitable for people with soy intolerance. 

Overall, if you’re looking for a quality CoQ10 supplement that’s easy to use, convenient, and effective, check out Nature’s Bounty.


Pros

  • + Laboratory-tested formula
  • + Natural colors
  • + Sodium-free

Cons

  • − Softgels may stick to each other

Solgar Vegetarian CoQ-10

Solgar Vegetarian CoQ-10 Solgar Vegetarian CoQ-10
star 9.5

Top Choice for Vegans

  • Form: Capsule
  • Number of servings: 15–30 servings
  • Ingredients: Coenzyme Q-10 (KanekaQ10 as ubiquinone), microcrystalline cellulose, silica, vegetable magnesium stearate, vegetable cellulose
  • CoQ10 content: 120 mg
  • Shipping policy: Free shipping with Amazon Prime; occasional limited-time deals on iHerb (e.g., free shipping on orders over $20)
$13.34 for 30 capsules
Visit Site Back To List

Finding the best CoQ10 supplement is challenging. And if you’re vegan, the process is even more nerve-racking. Fortunately, finding the right product, even for those with particular dietary restrictions, isn’t impossible.

For example, Solgar’s Vegetarian CoQ-10 is kosher and free from any animal-derived substances. 

Furthermore, it offers a decent dose of the highest-quality KanekaQ10® ubiquinone. Although it’s not as bioavailable as ubiquinol, it still provides pretty high absorption rates. 

Each vegetable capsule provides 120 mg of coQ10 as ubiquinone. So, if you’re looking for a mild yet highly effective formula, this could be the one for you.

While comparing the CoQ10 reviews of various brands, we noticed that many users praise Solgar’s formula for its purity. Namely, it doesn’t contain any artificial colors, preservatives, sweeteners, or flavors. Furthermore, it has no allergens like wheat, dairy, or gluten. 

So, this is a completely safe product, even for the more sensitive consumers.


Pros

  • + Suitable for people with sensitivities
  • + Sweetener-free
  • + Wheat-free

Cons

  • − High doses can cause stomach discomfort

Bluebonnet Nutrition CellularActive CoQ10

Bluebonnet Nutrition CellularActive CoQ10 Bluebonnet Nutrition CellularActive CoQ10
star 9.4

Best Allergen-Free Option

  • Form: Softgel
  • Number of servings: 30 servings
  • Ingredients: Kaneka Ubiquinol, medium-chain triglycerides, vegetarian capsules, sunflower lecithin, white beeswax, ascorbyl palmitate
  • CoQ10 content: 50 mg
  • Shipping policy: Free shipping with Amazon Prime; Occasional limited-time deals on iHerb (e.g., free shipping on orders over $20)
$12.76 for 30 softgels
Visit Site Back To List

If you’re looking for a highly bioavailable supplement without allergens, check out Bluebonnet Nutrition’s CellularActive CoQ10. 

This product is likely the best brand of CoQ10 for people with allergies because the formula is entirely free of some of the most common allergens. In other words, it contains no soy, gluten, dairy, crustacean shellfish, nuts, or wheat.

Additionally, it’s free of GMOs, sugar, and sodium. So, you won’t need to worry about safety.

The reviews for this affordable product containing ubiquinol, the best form of CoQ10, are also stellar. According to users, this product is excellent for clearing the mental fog and improving low energy levels. 

All this in no time. According to a user, this product can help increase mental alertness levels in as little as one month of use. 

On the downside, the softgels tend to be larger. So, we suggest having a big cup of water next to you for easier swallowing.


Pros

  • + Vegetarian-friendly
  • + Made with Kaneka Ubiquinol
  • + Non-GMO

Cons

  • − Softgels may be a bit large

Qunol Ultra CoQ10

Qunol Ultra CoQ10 Qunol Ultra CoQ10
star 9.3

The Most Absorbable Supplement

  • Form: Softgels
  • Number of servings: 120
  • Ingredients: Vitamin E, coenzyme Q10, medium-chain triglycerides, gelatin, polysorbate 80, dl-alpha tocopherol acetate, sorbitol, glycerin, soy lecithin, purified water, annatto suspension in sunflower oil
  • CoQ10 content: 100 mg
  • Shipping policy: Free shipping within the US
$29.97 for 120 softgels
Visit Site Back To List

What if we told you that you could achieve clear, glowing skin and excellent heart health using only one product—and fast? Qunol Ultra CoQ10 kills two birds with one stone thanks to the CoQ10-rich, vitamin-E-fortified E formula. 

In essence, it offers everything we expect from a best-quality CoQ10 supplement. 

This product provides three times better absorption than standard CoQ10 products. The reason for this is Ultra CoQ10’s unique formula, designed to allow CoQ10 to dissolve equally well in fat and water, which is not the case with regular supplements of this kind. 

Exceptionally high absorbability allows this top-rated CoQ10 product to show effect pretty quickly. While most CoQ10 supplements months to show results, Qunol Ultra CoQ10 can do so within weeks.

Finally, the only reason why we didn’t rank this product higher on our list is that it contains ubiquinone instead of ubiquinol. Nevertheless, it’s still an excellent product with a myriad of benefits.


Pros

  • + Three times better absorption
  • + Dairy-free
  • + Boosts skin health

Cons

  • − It doesn't contain ubiquinol
  • − Contains soy

Natural Factors Ubiquinol Active CoQ10

Natural Factors Ubiquinol Active CoQ10 Natural Factors Ubiquinol Active CoQ10
star 9.2

Best for Age-Related CoQ10 Loss

  • Form: Softgel
  • Number of servings: 30
  • Ingredients: CoQ10 Ubiquinol Form, organic flaxseed oil, gelatin, yellow beeswax, vitamin E
  • CoQ10 content: 200 mg
  • Shipping policy: Free shipping with Amazon Prime; Occasional limited-time deals on iHerb (e.g., free shipping on orders over $20)
$14.04 for 30 softgels
Visit Site Back To List

CoQ10 levels start gradually dropping in adulthood. It’s a natural process that occurs with age and results in lower energy levels, fatigue, skin elasticity loss, wrinkling, etc. 

To slow down the steady decline, you could resort to some of the best-quality CoQ10 supplements like Natural Factors Ubiquinol Active CoQ10. 

Thanks to the combination of 100 mg of the most bioavailable CoQ10 form and organic flaxseed oil, this product can effectively fight age-related fatigue and make you energized throughout the day. 

It also offers antioxidant protection, supports cardiovascular and cognitive health, reduces the risk of free radical damage, cardiovascular disease, and ensures sharp focus and mental clarity. 

Finally, this ubiquinol CoQ10 supplement comes with a potency and purity guarantee, vouching for its highest quality. It’s third-party tested and confirmed to be free of over 700 harmful substances.

Additionally, it’s free of preservatives, artificial colors, sweeteners, and allergens.


Pros

  • + Lab-tested for quality
  • + Includes organic flaxseed oil
  • + Reduces inflammation

Cons

  • − It may take time to show the results

21st Century Co Q-10

21st Century Co Q-10 21st Century Co Q-10
star 9.1

Best for Energy

  • Form: Liquid-filled softgel
  • Number of servings: 90
  • Ingredients: Coenzyme Q10, gelatin, soybean oil, beeswax, glycerin, lecithin, purified water, caramel
  • CoQ10 content: 100 mg
  • Shipping policy: Free shipping with Amazon Prime; occasional limited-time deals on iHerb (e.g., free shipping on orders over $20)
$15.90 for 90 softgels
Visit Site Back To List

If you’re looking for the best way to increase your energy levels, we suggest checking out the gluten-free 21st Century CoQ-10. This premium ubiquinol CoQ10 guarantees to provide sustained energy that’ll last you throughout the day and ward the fatigue away. 

You get 100 mg of CoEnzyme Q-10 in each softgel, and one pack should last you for three months. This is excellent news because you won’t need to order over and over again.

We also picked 21st Century Co Q-10 as one of the best CoQ10 brands because it provides excellent heart health support, like other high-quality products on our list. 

On the downside, if you want the fastest shipment option, this might not be the best option for you. According to some reviewers, shipment delays may happen.


Pros

  • + Small, easy to swallow capsules
  • + Three-month supply
  • + Numerous favorable customer reviews

Cons

  • − Shipment delays

How to Choose the Best CoQ10 Supplement: A Buyer’s Guide

Now that you got familiar with the best on the market, here’s a handy guide to assist your selection process. Here we’ll go through what CoQ10 is, its benefits, the potential side effects, recommended dosages, and the features to consider before choosing the right supplement. 

What’s CoQ10?

Coenzyme Q10 is a powerful vitamin-like antioxidant naturally occurring in humans, animals, and bacteria. It protects cells from oxidative stress damage and prevents and treats certain chronic illnesses. 

Namely, it’s typically used for heart-related conditions such as fluid build-up, heart failure, chest pain, or angina. Moreover, you can take CoQ10 for blood pressure issues.

Unfortunately, as we get older, our bodies’ natural CoQ10 production declines, leading to the need for supplementation.

Ubiquinone vs. Ubiquinol

Ubiquinone and ubiquinol are two different forms of CoQ10. Both are useful in their own way. For example, ubiquinol is more beneficial for those over 40, while ubiquinone may be well suited for those younger than 40. 

Ubiquinone naturally occurs in the body (with an estimated 95% of plasma coenzyme Q10 in ubiquinol form) and is readily absorbable. On the other hand, ubiquinone first has to be converted to ubiquinol in the body before absorption.

Coenzyme Q10 Benefits

CoQ10 is primarily used to slow down the aging process in the body. It’s also used to reduce inflammation, enhance heart health, etc. Here are some of the many perks of CoQ10 supplementation:

  • Energy levels boost
  • Focus improvement 
  • Eye health support
  • Heart health support
  • Fibromyalgia management
  • Nerve damage reduction
  • Oxidative stress protection
  • Skin nourishment
  • Reducing the frequency of mild migraines

Fertility

Several studies indicate that CoQ10 supplementation improves sperm quality, concentration, and activity. Therefore, CoQ10 supplements may be one of the ways to combat poor sperm quality, reduced sperm count, and infertility in men. 

CoQ10 and COVID

A recent study hinted that CoQ10 supplementation might have therapeutic benefits in reducing the adverse effects of coronavirus on the liver, kidney, and gastric tissue. Nevertheless, more research is required.

CoQ10 Side Effects

The adverse effects of using CoQ10 are mild and rare. If you experience any side effects, these may include heartburn, diarrhea, and nausea. 

Luckily, healthy individuals are at the lowest risk of developing side effects. However, people with liver or kidney problems and diabetes should be careful when using CoQ10, as it can lower blood pressure and blood sugar levels.

The Best Time to Take CoQ10

The best time for taking CoQ10 supplements is in the morning. If you take it close to bedtime, you may experience insomnia or disrupted sleep.

Recommended Daily Intake

Here are the recommended dosages:

  • Adults 40–60: 50–100 mg daily
  • Adults 60+: 100–200 mg daily
  • Patients on statin therapy: 100–200 mg daily
  • Patients diagnosed with congestive heart failure: 200–300 mg daily. 
  • Headaches: Children between 3 and 18 can take 1–3 mg (for three months)
  • CoQ10 deficiencies: 60–250 mg daily divided between 3 doses
  • Muscular dystrophy: Children aged 8–15 may take 100 mg daily (for three months)

How to Choose the Best CoQ10 Supplement

The market offers an overwhelmingly large number of CoQ10 supplements of varying quality. How to choose the best one? Here are some factors to look out for when shopping for the perfect supplement. We’ll mention bioavailability, ingredient quality, and other essential factors.

Form

Coenzyme CoQ10 comes in liquid, powder, softgel, gummy, tablet, or pill form.

Bioavailability

Prioritize products that contain ubiquinol, the most bioavailable form of CoQ10.

Purity

The best CoQ10 to take is pure and devoid of unnecessary fillers and additives, harmful ingredients, etc. It’s always a good idea to check whether the product has any third-party certification that would guarantee its purity, potency, and safety.

Price

CoQ10 supplements can be expensive. Therefore, we made sure to include options that offer the best value for the money. 

When assessing the price, consider the number of servings, the CoQ10 to added ingredients ratio, the quality of ingredients, and similar factors.

Conclusion

We hope this reviews list helped you get more familiar with CoQ10 supplementation benefits and find the best CoQ10 supplement for you and your family.

Taking care of your health and body, your home on this Earth, is essential, and CoQ10 is one of the nutrients required for your well-being. 

FAQ

Which CoQ10 is the most effective?

Ubiquinol is the most effective CoQ10 form. It’s up to eight times more effective than ubiquinone and other forms of CoQ10. 

The products containing ubiquinol on our list are Life Extension Super Ubiquinol CoQ10, Bluebonnet Nutrition CellularActive CoQ10, and Natural Factors Ubiquinol Active CoQ10. 

What brand of CoQ10 do doctors recommend?

The number one cardiologist-recommended brand of CoQ10 is Qunol. According to experts, Qunol is three times more absorbable than other standard forms of CoQ10. For the full review, check out the sections above.

What is the best form of CoQ10 for absorption?

Ubiquinol is the most absorbable CoQ10 form. Namely, it’s eight times more bioavailable than standard forms. 

Our top choice for CoQ10 with ubiquinol is Life Extension’s Super Ubiquinol CoQ10.

Which CoQ10 is better, ubiquinol or ubiquinone?

The body absorbs ubiquinol eight times more effectively than ubiquinone. Moreover, studies show that ubiquinol is more effective in treating fibromyalgia and heart failure. 

What is the best form of coenzyme Q10?

Ubiquinol is the best form of CoQ10 due to its high bioavailability. Nevertheless, it’s advisable to consult a healthcare professional for expert advice on the best CoQ10 for you.

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Hermina Drah

Hermina believes that every day is a chance to learn something new about the obscure world around us. The driving force behind her writing is her passion for sharing knowledge with others all around the world. After attaining her master’s degree in English language and literature, she has decided to join the team of creative writers dedicated to delivering the hottest content on the web. So what are Hermina’s favorite topics to cover? Animals, good books, health, fitness, self-care—you name it.

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