The Best Digestive Enzymes for Your Stomach in 2022

There are several reasons why Zenwise® Health Digestive Enzymes is the highest-rated digestive enzymes supplement on our list. 

First, it contains a variety of enzymes, including the main three—amylase, protease, and lipase. These proteins help break down foods faster, make nutrient absorption more efficient, and prevent indigestion.

Numerous digestive enzymes reviews confirm that this supplement effectively breaks down even heavy meals and hard-to-digest foods. Therefore, this product is particularly beneficial for individuals over 20, whose body’s ability to produce enzymes started to decrease gradually.

Stomach pain, flatulence, bloating, chronic constipation, and nausea are only some of the problems this enzyme blend can help solve.

Second, these top-rated digestive enzymes contain a strain of clinically proven probiotics that further enhance digestion and promote overall gut health and immune system function. 

Finally, it’s a very cost-effective supplements brand made predominantly with plant-based ingredients to make it suitable for vegetarians.

Pure Encapsulations® Digestive Enzymes also rank high on the list of the best products on the market for people suffering from digestive problems. 

Like other good digestive enzymes products, it prevents digestive issues by helping you digest various foods—carbs, proteins, fats, dairy, etc. According to the consumer reviews, besides bloating and indigestion, this product also helps with pancreatitis.

What’s unique about this product is that it’s made with highly sensitive consumers in mind. It uses only pure, hypoallergenic ingredients, so you can be sure you’re safe from allergic reactions. 

It’s free of the most common allergens such as egg, wheat, gluten, peanuts, and tree nuts. Additionally, it doesn’t contain papain or pork gelatin—the allergenic ingredients are often found in digestive enzymes supplements.

Additionally, it doesn’t contain any unnecessary fillers, artificial colors, or GMOs.

This one-of-a-kind formula is made with 18 different plant-based digestive enzymes and provides a wide array of benefits. 

Like other good digestive enzymes, this product is effective against an array of digestive issues commonly occurring after meals. Gas, bloating, and indigestion are only some of the problems EnzymeMD helps solve.

However, these top digestive enzymes don’t only aid digestion. They also promote weight loss, according to customer reviews. 

Lastly, 1MD™ is a reputable company that sources the ingredients from safe, clinically-researched ingredients. Therefore product quality is guaranteed.

Wholesome Wellness offers another high-quality digestive enzymes formula stacked with prebiotics and probiotics for optimal gut health and immune system support. 

While this isn’t the only digestive enzyme supplement that contains probiotics, countless reviews claim it’s one of the best digestive enzymes for gas and cleansing your gut of harmful bacteria.

This digestive enzyme formula is effective against bloating and flatulence. Additionally, it offers excellent pancreatic, fat, and bowel cleansing due to the inclusion of organic turmeric, ginger, papaya, and other ingredients.

The inclusion of a wide array of different enzymes enables this product to digest a wide range of food, whether raw, spicy, processed, or fried.

This high-quality digestive enzymes formula is made in the US in a GMP-certified and third-party tested facility. It’s also free of allergens like gluten, soy, gelatin, shellfish, ox, peanuts, and eggs.

Lastly, it also qualifies among the best digestive enzymes for vegans, as it features an organic, entirely plant-based vegan formula.

All products on our reviews list are effective against digestive discomfort caused by conditions such as IBS, GERD, SIBO, etc. 

However, Dr. Matthew #1 Digestive Enzymes stood out as the best digestive enzymes for IBS due to the overwhelming number of positive customer reviews highlighting this feature. 

Consumers emphasize its effectiveness in providing IBS relief and eliminating symptoms such as gas, bloatedness, constipation, diarrhea, etc. Furthermore, this product proved helpful in treating digestive issues caused by gallbladder removal. 

This unique formula contains 19 enzymes in total. It’s also up to six times more potent than regular blends when it comes to digesting lactose and similar foods, making it one of the most effective digestive enzymes on our list. 

Finally, this 100% natural, gluten-free, and vegetarian-friendly US-made product features a pleasant peppermint flavor that leaves no unpleasant aftertaste upon consumption.

Doctor’s Best® is another brand of digestive enzymes that helps combat a wide range of digestive problems. It contains 90 gluten-free, non-GMO capsules ideal for vegetarians that provide a solution for a broad spectrum of digestive issues.

This top-rated digestive enzymes supplement aids the digestion of various types of food. The full-spectrum enzyme blend easily breaks down proteins, carbohydrates, and fats in both raw and cooked food, preventing flatulence, bloating, and other digestive issues. 

Furthermore, beta-glucanase helps break down food generally harder to digest—grains, beans, and other vegetables. At the same time, this high-quality digestive enzymes supplement is also abundant in invertase and glucoamylase that promote the easy digestion of sugars.  

Last but not least, the inclusion of probiotic bacteria (Bacillus subtilis) greatly helps with alleviating abdominal discomfort. These friendly bacteria ensure optimal gut health and boost the immune system.

SIBO and GERD can truly turn your life and eating habits upside-down. Stomach pain, nausea, and bloating are only some of the symptoms that can occur and turn eating from a pleasant event into something that creates discomfort.

These top-rated digestive enzymes offer an array of beneficial ingredients, including enzymes that could help alleviate SIBO and GERD symptoms. But that’s not all. 

Super Enzymes also qualify as one of the best digestive enzymes for constipation and poor digestion that can occur after gallbladder removal surgery. Consumers report feeling relief in less than two weeks of the treatment. 

This is one of the best US-made digestive enzymes manufactured by a family-owned company founded in 1968. They put much effort into ensuring the proper manufacturing conditions, which is corroborated by the NPA certification.

Lastly, these high-quality digestive enzymes are keto-friendly and free of allergens such as gluten, soy, nuts, wheat, eggs, fish, and dairy.

Dr. Tobias™ Digestive Enzyme, one of the most effective digestive enzymes on the market, contains 18 different plant-derived enzymes. 

Due to the different enzymes’ high number and activity level, this formula effectively digests a wide range of nutrients such as protein, sugar, fiber, lactose, fat, gluten, etc. This means you can eat meat, dairy, broccoli, and other generally hard-to-digest food with no worries. 

Notably, due to its high lipase content, this could be the best supplement for those who have difficulties digesting fatty foods. According to digestive enzymes supplement reviews, it helps reduce heartburn and other stomach disturbances associated with fatty food consumption.

Moreover, some consumer reviews rate it as one of the best digestive enzymes for post gallbladder surgery, as it helps resolve bloating, nausea, and acid reflux that often accompany gallbladder removal.

Additionally, this product is made from non-GMO ingredients and third-party-tested for effectiveness, ingredient purity, nutritional value, and label accuracy.

This blend is targeted at various digestive problems, including bloating, IBS, constipation, and gas. It’s manufactured by one of the best US supplement companies, with over 35 years of experience in the industry.

Essential Enzymes, one of the best-rated digestive enzymes, is made with non-GMO ingredients. It includes plenty of enzymes that digest a wide variety of foods, support your gut health, and boost your energy levels.

One of the main features of these top enzyme supplements is the time it takes for the supplement to start working. If you want to eat your meals immediately after taking a supplement, this is the best choice for you. There’s no delay—you can start eating immediately after taking it.

To cap it all, you can also get creative with it. If you find swallowing pills arduous, you can open the capsule and sprinkle its content all over your food. Just make sure it’s not hot, as heat can affect enzymes’ activity.

MAV Nutrition presents us with the ultimate digestion issues solution in a capsule form. Like other top-rated digestive enzyme supplements, this product is effective against common digestive issues such as constipation and bloating. 

The inclusion of probiotic bacteria and various digestive enzymes for IBS and diarrhea relief keeps your gut healthy and distress-free. 

With MAV Nutrition Best Enzymes, you can feast on your favorite food (even the one that’s hard to digest) guilt-free. This is because it’s packed with enzymes covering a broad spectrum of ingredients.

Most importantly, this product can help you feel more energetic. Keeping your gut healthy will allow your body to absorb nutrients more effectively and prevent wasting excessive amounts of energy on digestion. 

Finally, these non-GMO capsules are one of the easiest to swallow.