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The Best Glutathione Pills In 2022

  • Dorcas Ayodele
  • April 26, 2022
glutathione

If you’re on the market for a glutathione supplement to help boost your immune system, detoxify your liver, care for your skin, or other health benefits—look no further!

We’ve done the research in order to present you with concise reviews and a comprehensive buyers guide for the best glutathione pills available.

So, keep reading to find out which brand is right for you!

Top 10 Glutathione Brands in 2022

We’re committed to providing you with the best products available. If you purchase through one of the links on our site, we may earn a commission. Read our full Affiliate Disclosure.

Nutrivein Liposomal Glutathione Setria® 700mg

Nutrivein Liposomal Glutathione Setria® 700mg Nutrivein Logo

Editor’s choice

  • Tasteless
  • Easy to swallow
  • Hypoallergenic
star 9.9
$34.99 for 60 capsules Read Review
Visit Site

Puritan’s Pride L-Glutathione

Puritan’s Pride L-Glutathione Puritan's Pride Logo

Best Rapid Release Product

  • Has anti-aging properties
  • Non-GMO
  • Sugar- and sodium-free
star 9.8
$29.99 for 30 capsules Read Review
Visit Site

Life Extension Glutathione, Cysteine & C

Life Extension Glutathione, Cysteine & C Life Extension Logo

Top choice for liver function

  • Scientifically validated formula
  • No additives
  • Gluten-free
  • Non-GMO
star 9.6
$16.50 for 100 capsules Read Review
Visit Site

Pure Encapsulations Liposomal Glutathione

Pure Encapsulations Liposomal Glutathione Pure Encapsulations Logo

Top liposomal glutathione

  • Highly bioavailable
  • Hypoallergenic
  • Non-GMO
star 9.5
$54.20 for 30 capsules Read Review
Visit Site

NOW Glutathione 500 mg

NOW Glutathione 500 mg NOW Logo

Best choice with milk thistle extract

  • Vegan-friendly
  • Sourced from high-quality nutrients
  • Contains milk thistle extract
star 9.3
$23.99 for 30 capsules Read Review
Visit Site

Relumins Advance White 1650mg Glutathione Complex – 15x

Relumins Advance White 1650mg Glutathione Complex – 15x Relumins Logo

Best glutathione for skin

  • Vegan-friendly
  • Proven safe
  • Effective oral Glutathione formula available
star 9.1
$79.00 for 90 capsules Read Review
Visit Site

Bulletproof Glutathione Force

Bulletproof Glutathione Force Bulletproof Logo

Top for detox support

  • Supports detoxification
  • Soy-free
  • Dye-free
  • Vegan-certified
star 9.0
$59.95 for 90 capsules Read Review
Visit Site

Double Wood S-Acetyl L-Glutathione

Double Wood S-Acetyl L-Glutathione Double Wood Logo

Highly bioavailable glutathione

  • Soy-free
  • Gluten-free
  • Non-GMO
  • Highly recommended by consumers
star 8.9
$29.95 for 60 capsules Read Review
Visit Site

Thorne Glutathione-SR

Thorne Glutathione-SR Thorne Logo

Top Choice for Athletes

  • Contains no soy, dairy, yeast, or fish
  • Made with the purest ingredients
  • NSF certified
star 8.6
$43.00 for 60 capsules Read Review
Visit Site

Dr. James Advanced Glutathione Formula

Dr. James Advanced Glutathione Formula Dr. James Logo

Top product for skin whitening

  • No preservatives
  • GMP-certified
  • 100% natural ingredients
star 8.8
$39.99 for 60 capsules Read Review
Visit Site

Our Top-Rated Glutathione Pills Reviews

In the next section, you’ll learn more about the top glutathione brands, including prices, ingredients, and some of their benefits and drawbacks. 

Let’s dive in!

Nutrivein Liposomal Glutathione Setria® 700mg

Nutrivein Liposomal Glutathione Setria® 700mg Nutrivein Liposomal Glutathione Setria 700 mg
star 9.9

Editor’s choice

  • Type: Capsule
  • Ingredients: Setria® L-Glutathione, phospholipid complex (from non-GMO sunflower oil and lecithin), vegetable cellulose capsule
  • Shipping policy: Free standard shipping fee
  • Return policy: 30-day money-back guarantee
  • Discounts (or any other buying perks): Subscribe and save 10%
$34.99 for 60 capsules
Visit Site Back To List

Nutrivein Liposomal Glutathione Setria® 700mg is ranked the best glutathione supplement of 2022 on our list! It’s often characterized by its optimal absorption, quality, and effectiveness. 

This all-natural supplement primarily consists of purely reduced glutathione. Therefore, it’s a powerful antioxidant for liver detox, brain function support, and cardiovascular function maintenance. 

It can also help reduce inflammation related to physical activity, health issues, or aging. What’s more, it can also be used for hangover prevention.

This brand can also enhance the skin, giving it a bright and youthful look, even promoting skin whitening by preventing melanin synthesis. 

Other perks of this glutathione supplement include cellular metabolism boost and all-natural immune system support. Overall we believe Nutrivein offers some of the best glutathione in the USA. They’re tasteless, easy to swallow, and contain no animal products.


Pros

  • + Tasteless
  • + Easy to swallow
  • + Hypoallergenic

Cons

  • − May cause bloating

Puritan’s Pride L-Glutathione

Puritan’s Pride L-Glutathione Puritan’s Pride L-Glutathione 500 mg
star 9.8

Best Rapid Release Product

  • Type: Capsules
  • Ingredients: L-Glutathione, gelatin, vegetable cellulose, silica, vegetable magnesium stearate
  • Shipping Policy: Free standard shipping on orders over $49
  • Return policy: 90-day money-back guarantee
  • Discounts (or other buying perks): Order one bottle and get two additional for free, or order two bottles and get four for free; save 15% by signing up for emails
$29.99 for 30 capsules
Visit Site Back To List

Puritan’s Pride has been providing caring service and quality vitamins since 1973, establishing an enviable reputation by continually helping consumers maintain their overall wellness.

This company creates excellent quality products by using only the best ingredients to satisfy its customers. 

Like all Puritan Pride Products, L-Glutathione undergoes up to 15 testing sessions before being released onto the shelves to ensure maximum quality, safety, and potency. This supplement also protects muscles from oxidative stress, making it excellent for gym enthusiasts.

Moreover, its rapid release system ensures a fast onset of action and a quick increase in energy levels. So, if you’re always on the go, this might be the best pick for you.


Pros

  • + Has anti-aging properties
  • + Non-GMO
  • + Sugar- and sodium-free

Cons

  • − Some customers complained of an unpleasant odor upon opening

Life Extension Glutathione, Cysteine & C

Life Extension Glutathione, Cysteine & C Life Extension Glutathione, Cysteine & C
star 9.6

Top choice for liver function

  • Type: Capsule
  • Ingredients: Ascorbic acid (500 mg), Setria® L-Glutathione (reduced, 50 mg), L-cysteine hydrochloride (200 mg), vegetable cellulose (capsule), microcrystalline cellulose, stearic acid, silica
  • Shipping Policy: Free shipping on AutoShip orders
  • Return policy: One-year money-back guarantee
  • Discounts (or any other buying perks): Save 18% on AutoShip orders
$16.50 for 100 capsules
Visit Site Back To List

The liver is the largest internal organ, and its importance can’t be overemphasized. For instance, one of its primary roles is keeping the body healthy by eliminating toxins. 

However, the liver gradually loses function over time and may require some help and rejuvenation. This is where glutathione supplements like Life Extension Glutathione, Cysteine & C come into play. 

This product stands out as the most effective glutathione pill for liver health for many reasons, the most important of which is its unique formula. Plus, Life Extension is a well-reputed household name in the industry lauded for delivering outstanding, high-quality products. 

Its three active components (L-cysteine, glutathione, and vitamin C) serve as a triple-action free radical protection and help promote optimal liver function. 

Life Extension Glutathione, Cysteine & C is one of the few glutathione supplements formulated with L-cysteine. This non-essential amino acid supports many bodily processes, including protein synthesis and glutathione production. 

Additionally, it contains vitamin C, which, along with glutathione, helps protect cells from oxidative stress, supports healthy iron absorption, and more.

Another reason that we liked this product is that it received many positive reviews and recommendations from satisfied customers, confirming its quality and effectiveness.


Pros

  • + Scientifically validated formula
  • + No additives
  • + Gluten-free
  • + Non-GMO

Cons

  • − May cause gastrointestinal disturbances in consumers w/ a sensitive stomach

Pure Encapsulations Liposomal Glutathione

Pure Encapsulations Liposomal Glutathione Pure Encapsulations Liposomal Glutathione
star 9.5

Top liposomal glutathione

  • Type: Capsule
  • Ingredients: BioGlute proprietary blend of glutathione and essential phospholipids (Setria glutathione, phospholipid complex), gelatin capsule, extra virgin olive oil, beeswax, soy
  • Shipping Policy: Free shipping on orders over $100
  • Return policy: 30-day returns policy; 7-day policy for damaged items
  • Discounts (or any other buying perks): Save $12.90 by ordering two bottles at once
$54.20 for 30 capsules
Visit Site Back To List

Pure Encapsulation is well known for its fantastic array of supplements, and Liposomal Glutathione is no exception. That’s why it made its way to our top five most effective glutathione supplement brands. 

This potent antioxidant formula is intended to promote and support cellular function, liver detoxification, and more. Plus, it can help your cells maintain healthy lipid metabolism. 

Moreover, its unique liposomal formula can protect glutathione bonds from degradation in the gut, preserve glutathione’s function, support absorption, and enhance its bioavailability.

As its name suggests, Pure Encapsulations includes only the purest, high-quality ingredients from reliable suppliers in their products. Therefore they abstain from using GMOs, unnecessary preservatives, binders, shellacs, or coating. 

This product is also free of artificial colors, flavors, sweeteners, and many common allergens (e.g., gluten, peanuts, tree nuts, eggs, wheat, etc.)

Finally, Liposomal Glutathione is tested for potency and purity, so it’s undoubtedly safe and effective.


Pros

  • + Highly bioavailable
  • + Hypoallergenic
  • + Non-GMO

Cons

  • − A bit pricey

NOW Glutathione 500 mg

NOW Glutathione 500 mg NOW Glutathione 500 mg
star 9.3

Best choice with milk thistle extract

  • Type: Capsule
  • Ingredients: Glutathione, alpha-lipoic acid, milk thistle extract, microcrystalline cellulose, cellulose capsule, silicon dioxide, and magnesium stearate (vegetable source)
  • Shipping Policy: Free shipping on orders of a minimum of $50 within the continental US and DC
  • Return policy: 30-day return policy
  • Discounts (or any other buying perks): Save $3.99 by ordering a 60-capsule bottle; coupons
$23.99 for 30 capsules
Visit Site Back To List

NOW, is also one of the best glutathione supplement brands on our list. However, its use of milk thistle extract as a complimentary ingredient sets it apart from other products we reviewed.

It also features another antioxidant as a complementary ingredient—alpha-lipoic acid. 

NOW Glutathione supports healthy immune function and detoxification processes like other quality supplements. Yet, it also plays a vital role in maintaining cellular health by neutralizing free radicals and enhancing the presence of vitamins C and E.

Moreover, NOW Glutathione is sourced from high-quality ingredients to ensure its effectiveness. Since this product also tries to meet many dietary needs, it’s devoid of gluten, egg, dairy, nuts, and other potential allergens. 

This supplement is also vegan/vegetarian friendly and kosher.


Pros

  • + Vegan-friendly
  • + Sourced from high-quality nutrients
  • + Contains milk thistle extract

Cons

  • − May cause upset stomach
  • − Some customers reported receiving packages with broken seals

Relumins Advance White 1650mg Glutathione Complex – 15x

Relumins Advance White 1650mg Glutathione Complex – 15x Relumins Advance White 1,650 mg Glutathione Complex – 15x
star 9.1

Best glutathione for skin

  • Type: Capsule
  • Ingredients: Vitamin E, riboflavin, selenium, L-Glutathione, green tea 4:1 extract, L-methionine, rose hips, N-acetyl-L-cysteine, alpha-lipoic acid, milk thistle seed 4:1 extract, citrus bioflavonoid complex (from orange, lemon, and grapefruit peel), bitter orange fruit extract (40% hesperidin), Sophora Japonica bud extract (95% quercetin dihydrate), soybean extract, vegetable cellulose (capsule), magnesium stearate, silicon dioxide, microcrystalline cellulose
  • Shipping Policy: Standard shipping fee applies
  • Return policy: 30-day return policy
  • Discounts (or any other buying perks): Limited-time discounts
$79.00 for 90 capsules
Visit Site Back To List

Are you worried that your skin is beginning to show signs of aging? If so, Relumins L-Glutathione complex could be the brand for you, as it has the most advanced glutathione formula for skin rejuvenation.

Relumins Advance White 1,650 mg Glutathione Complex helps fight free radicals that cause skin damage and promotes proper liver function. Moreover, it contains vitamins C and E, which have potent anti-inflammatory properties and thus help to reduce stress. 

Although these supplements are marketed as whitening glutathione pills, they’re also incredibly effective at repairing and rejuvenating the skin. Furthermore, the additional boost of Alpha Lipoic Acid has been shown to naturally boost glutathione levels in the body. 

Plus, you can rest assured knowing that each capsule has been tested for purity, effectiveness, nutritional value, and ingredient safety in numerous clinical studies.


Pros

  • + Vegan-friendly
  • + Proven safe
  • + Effective oral Glutathione formula available

Cons

  • − Some customers complained of abdominal cramps

Bulletproof Glutathione Force

Bulletproof Glutathione Force Bulletproof Glutathione Force
star 9.0

Top for detox support

  • Type: Capsule
  • Ingredients: Glutathione, palmitic acid, phosphatidylcholine, modified cellulose (vegetable capsule), oleic acid
  • Shipping policy: Free standard shipping on orders over $35
  • Return Policy: 30-day return policy
  • Discounts (or any other buying perks): Save 10% on all subscription purchases
$59.95 for 90 capsules
Visit Site Back To List

Bulletproof Glutathione Force contains the most effective form of glutathione to boost your immune system and support your body’s ability to process toxins. 

These capsules are designed to protect glutathione from denaturation in the stomach, ensuring safe delivery to the small intestine. Moreover, Bulletproof Glutathione Force helps rid your body of toxins, relieve stress, and improve cellular function. 

By taking up to three capsules a day, you’ll reap the rewards of having a detoxified and optimally functioning liver, an improved immune system, and other health benefits.

Like most products on our product list, Bulletproof Glutathione Force is free from sugar, gluten, and soy and tested for purity and potency.


Pros

  • + Supports detoxification
  • + Soy-free
  • + Dye-free
  • + Vegan-certified

Cons

  • − Bitter taste

Double Wood S-Acetyl L-Glutathione

Double Wood S-Acetyl L-Glutathione Double Wood S-Acetyl L-Glutathione
star 8.9

Highly bioavailable glutathione

  • Type: Capsule
  • Ingredients: S-Acetyl L-Glutathione, gelatin capsule, microcrystalline cellulose
  • Shipping policy: Free shipping with USPS First Class
  • Return policy: A 30-day money-back guarantee on unopened items
  • Discounts (or any other buying perks): Save 25% on subscription orders
$29.95 for 60 capsules
Visit Site Back To List

The key ingredient in this supplement (S-Acetyl L-Glutathione), makes it one of the most effective glutathions currently available. Double wood S-Acetyl L-Glutathione is a highly bioavailable variant for oral absorption due to its acetyl properties. 

This means that it remains intact in the gut, which allows a greater concentration to be absorbed into the bloodstream, ensuring maximum effectiveness.

From the age of 45, the body begins to produce less glutathione. Although the liver has some reserves, it gradually loses some of its ability to function as aging occurs. 

Hence, it becomes crucial to find a suitable supplement. Various reviews from customers who have used this product have indicated how effective it can improve the liver’s detoxification.

Because it’s a powerful intracellular antioxidant that supports cell and immune system health, Double wood S-Acetyl L-Glutathione is also one of the most reviewed products the USA. 


Pros

  • + Soy-free
  • + Gluten-free
  • + Non-GMO
  • + Highly recommended by consumers

Cons

  • − Some consumers complained it caused abdominal pain

Thorne Glutathione-SR

Thorne Glutathione-SR Thorne Glutathione-SR
star 8.6

Top Choice for Athletes

  • Type: Capsules
  • Ingredients: Glutathione, silicon dioxide, high and low viscosity hydroxypropyl methylcellulose, calcium laurate, leucine, hypromellose capsule, magnesium citrate
  • Shipping policy: Free shipping in the continental US
  • Return policy: 60-day satisfaction guarantee
  • Discounts (or any other buying perks): Subscribe and save 10% on refills
$43.00 for 60 capsules
Visit Site Back To List

It’s well known that a normal range of glutathione in the body can help support the liver, pulmonary, and immune functions as well as improving cognitive, cardiovascular, eye, and gut health.

However, it’s important to note that strenuous exercise can lower blood glutathione levels and create oxidative stress, causing damage to cells. 

Therefore athletes can greatly benefit from glutathione supplementation. Moreover, Glutathione is NSF-certified for sport, meaning it doesn’t contain substances banned by major athletic organizations. 

Throne Glutathione-SR is an antioxidant that directly destroys several reactive free radicals in the body and acts as a cofactor in dozens of enzymatic reactions involved in detoxification.

It’s one of the best glutathione pills because its sustained-release formula inhibits it from being destroyed by stomach acid and digestive enzymes. This allows for a slower release and a more steady level in the bloodstream.

Also, this product is made with the purest ingredients and without gluten or other major allergens (eggs, tree nuts, peanuts). It’s also free from soy, dairy, yeast, or fish. 


Pros

  • + Contains no soy, dairy, yeast, or fish
  • + Made with the purest ingredients
  • + NSF certified

Cons

  • − Some users complained of allergic reactions

Dr. James Advanced Glutathione Formula

Dr. James Advanced Glutathione Formula Dr. James Advanced Glutathione Formula
star 8.8

Top product for skin whitening

  • Type: Capsule
  • Ingredients: L-glutathione, alpha-lipoic acid, thioctic acid, malic acid, niacinamide, licorice root
  • Shipping Policy: $12.80 shipping fee for all orders
  • Return policy: 30-day return policy
  • Discounts (or any other buying perks): None
$39.99 for 60 capsules
Visit Site Back To List

If you’ve been considering trying glutathione for skin whitening, then Dr. James Advanced Glutathione Formula might be the brand for you.

It effectively removes dark spots, freckles, age spots, scars, and other blemishes, giving your skin a light glow and a healthy appearance. So, it’s excellent for those who want to maintain fair, radiant skin and reverse the effects of aging. 

This supplement is an excellent detoxifier due to its powerful antioxidant properties. Furthermore, each capsule contains pure natural glutathione made from 100% natural ingredients and is suitable for men and women alike. 

Overall, we believe this product is the best glutathione brand for skin whitening. Amazingly, if taken as recommended, you can expect to see results in as little as four weeks.


Pros

  • + No preservatives
  • + GMP-certified
  • + 100% natural ingredients

Cons

  • − Many poor reviews

 

How to Choose the Best Glutathione Supplement: A Buyer‘s Guide

With so many available options, choosing the best glutathione supplement can be quite a challenge, especially if you’re a first-time buyer. 

So, we’ve created the guide below to fill you in on a few things that you should watch out for when deciding which brand is most suitable for your particular needs.

Let’s check it out!

What is Glutathione?

Glutathione is a highly potent antioxidant found in plants, animals, and fungi. It’s composed of mostly three amino acids—glutamic acid, cysteine, and glycine and is produced by our livers and cells in the central nervous system.

This substance plays a vital role in the body’s metabolic processes by eliminating free radicals, which, if accumulated, lead to oxidative cell damage, inflammation, and various health issues.

Unfortunately, our glutathione levels can diminish due to certain health issues (i.e., cancer, diabetes type2) and as we get older. However, we can take the most effective glutathione supplements (such as those from our reviews above) to increase our levels and overall health.

Glutathione Supplement Forms

Glutathione, similar to other supplements, comes in different forms: 

  • Tablet
  • Liquid
  • Capsule
  • Injection

Tablets are generally easy to use and store but may be challenging to swallow for some. Additionally, only about 25% of the supplement gets absorbed into the systemic circulation due to the first-pass effect. 

Softgel capsules are easier to swallow than tablets and are also more bioavailable.

Liquid glutathione is the easiest to swallow, making it particularly convenient for children and individuals who find it challenging to ingest pills and tablets. Plus, it’s also more bioavailable than both capsules and tablets.

Injectable glutathione is quite an uncommon but very effective form and the most bioavailable.

Glutathione Supplements Benefits

Some of the essential benefits of the glutathione include:

  • Reduces oxidative stress 
  • Reduces cell damage reduction in fatty liver disease
  • Boosts Insulin resistance in seniors
  • Decreased muscle fatigue 
  • Psoriasis improvement
  • Skin whitening and lightening
  • May help fight symptoms of respiratory disease

Side Effects

So far, no severe side effects related to glutathione consumption have been documented. However, it’s vital to consult a physician before taking any supplements.

The most common side effects are:

  • Allergic reactions 
    • Rash 
    • Hives 
    • Itching
    • Wheezing
    • Difficulty breathing
    • Angioedema (swelling of lips, tongue, or face)
  • Bloating
  • Abdominal cramps

Conclusion

The aim of our glutathione pills reviews and guide was to present our readers with what we believe to be the best brands currently available and discuss each one’s specific features. 

We hope that we’ve succeeded and that you’re now equipped with the proper information to find the correct pills for your particular needs. However, please remember to consult a physician before using a supplement.

FAQ

Which brand of glutathione is best? 

The answer to this question depends on various factors, primarily your specific needs and expectations. However, Nutrivein Liposomal Glutathione Setria® stood out as the best due to its quality, effectiveness, and range of action.

Nonetheless, we believe that all products on our list of the top glutathione supplements are high-quality and effective. 

What are the best glutathione pills for skin whitening? 

Our research and various positive customer reviews have led us to believe that Dr. James Advanced Glutathione Formula is the best glutathione supplement for skin whitening.

How much glutathione to take for skin whitening? 

There isn’t a universal dosage for solving this kind of dermatological issue. The glutathione dosage for skin whitening will largely depend on how much skin discoloration you have. 

However, according to studies, taking 500 mg of glutathione per day over an extended period (e.g., four weeks) may help with skin lightening. 

Do glutathione tablets really work?

Research and numerous consumer testimonials confirm glutathione supplements may be an effective treatment for various conditions. 

Taking the best glutathione pills can help improve your skin, detox your liver, improve your immune function, etc. However, it’s important to consult your doctor before taking any supplements.

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Dorcas Ayodele

Dorcas is a student nurse and content writer. As a health enthusiast, she loves to research and write about various topics in this niche that feed her knowledge and enlighten others. Music soothes her mind and helps her destress. Aside from writing content, she enjoys reading books and watching movies.

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